The plot follows an initially insecure sorority girl named Allison Ruth, who finds herself thrown into a plot many thousands of worlds larger than her. After Allison is forcibly given a powerful fragment of this setting's gods, called a "key", instead of her unstable boyfriend, she discovers that she – alongside a demon named Cio and an angel named White Chain – must fight through a council of seven other keyholders – known as demiurges – who currently rule the multiverse, in order to save her boyfriend